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Novel Maturation‐defective Attenuated Chlamydia Vaccine
Invention Summary:
Millions of American men and women are infected with Chlamydia each year. Without proper treatment, a substantial proportion of chlamydia-infected women may develop infertility and other health problems. To date, no Chlamydia vaccine is available.
Chlamydia is an obligate intracellular bacterium with a unique...
Published: 7/28/2022
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Inventor(s): Huizhou Fan
Keywords(s):
Category(s): Technology Classifications > Vaccine, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease
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A NOVEL METHOD OF GENERATING LIVE-ATTENUATED REPLICATION-DEFECTIVE DNA VIRUSES FOR VACCINE DEVELOPMENT
Method for Generating Replication-Defective DNA Virus for Safer Live-Attenuated VaccinesPrimary Inventor: Hua Zhu, Ph.D.Department of Microbiology, Biochemistry, and Molecular Genetics RU Tech ID #: 2021-002 Invention Summary: Live-attenuated vaccines are widely used for immunization against many viral diseases. However, there are still...
Published: 12/8/2021
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Inventor(s): Hua Zhu, Dabbu Jaijyan, Moses Lee
Keywords(s): Antiviral
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Vaccine
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Deposition of Microscale Coatings by Self-Limiting Electrospray
a. Overview of thickness-limited electrospray deposition (ESD). Electrostatically-driven spray creates a charged film which redirects charged incident droplets. b. and c. SEM images of spray results, illustrating the wide range of morphologies and particle size which can be obtained with this method(b: nanowires, c: hollow spheres).Invention Summary:...
Published: 12/8/2021
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Inventor(s): Jonathan Singer, Lin Lei
Keywords(s): Drug Delivery
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > COVID-19, Technology Classifications > Medical Devices, Technology Classifications > Vaccine
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A Novel Vaccine Candidate Against Fungal Infection
Vaccination with a heat-killed mutant strain offers cross-protection against diverse fungal infections in a mouse model, significantly improving survival. A.) Mice vaccinated at different doses show higher survival rates when challenged with a wild strain (H99) of fungus. B.) Vaccinated mice are protected from infection by C. gattii R265 and have significantly...
Published: 12/8/2021
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Inventor(s): Chaoyang Xue, Amariliz Rivera
Keywords(s): Proteins
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Vaccine
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