Search Results - rene+schloss

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Multilayer Stackable Tissue Culture Platform for 3D Co-Culture Invention Summary: In a native tissue inside an animal, different types of cells co-exist and communicate with one another through the surrounding microenvironment using chemical and mechanical signaling. The lack of technology to recreate such a microenvironment in in vitro models results in either under or over prediction of results using conventional... Published: 7/28/2022   |   Inventor(s): Martin Yarmush, Anil Shrirao, Rene Schloss, Ileana Marrero-Berrios Keywords(s):   Category(s): Technology Classifications > Research Tools, Technology Classifications > Physical Sciences & Engineering

In Vitro Model of Liver Steatosis for Screening of Drug Compounds The decrease in liver steatosis in hepatocytes cultured in steatosis reducing medium.Invention Summary: Donor livers are frequently rejected due to high intracellular fat content, called steatosis, which increases the risk of primary graft non-function in transplant patients. Because liver transplantation remains the only effective treatment for end-stage... Published: 12/8/2021   |   Inventor(s): Martin Yarmush, Nir Nativ, Francois Berthiaume, Gabriel Yarmush, Timothy Maguire, Rene Schloss Keywords(s): Drug Discovery/Screening Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools