Search Results - sanjay+tyagi

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High-fidelity amplified FISH (amp-FISH) for sensitive and specific in situ detection of RNA amp-FISH probes can distinguish single-nucleotide variations within single mRNA molecules and produces amplified signals in situ for both mutant and wild-type variants, each in a distinct color.Invention Summary:Fluorescence in situ hybridization (FISH) is used in clinical and research applications to detect and visualize specific nucleic acid targets... Published: 12/8/2021   |   Inventor(s): Sanjay Tyagi, Salvatore Marras Keywords(s): Sensors & Probes Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Diagnostics

High-throughput gene expression screening in activated T-cells using FISH-Flow Induction of gene expression and subsequent detection by FISH-Flow. c-fos expression is induced in activated cells, which are readily identified by FISH-Flow. GFP: negative control, GAPDH: positive control. Invention Summary: Researchers at Rutgers have developed an assay combining the analytical power of flow cytometry and fluorescence in situ... Published: 8/22/2022   |   Inventor(s): Yuri Bushkin, Maria Gennaro, Sanjay Tyagi, Richard Pine Keywords(s): Sensors & Probes Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics