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Predicting Therapeutic Resistance to Tamoxifen in Cancer Treatment
Summary:
Currently, patients with ER+ breast cancer are administered tamoxifen without considering their potential response to this therapy. Thousands of women take the tamoxifen only to discover that their tumors do not respond or that they develop resistance over time. The ability to screen patients ahead of the therapy administration can improve...
Published: 12/8/2021
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Inventor(s): Antonina Mitrofanova, Sarra Rahem
Keywords(s): Bioinformatics, Breast Cancer, Data Science, Digital Health
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Diagnostics, Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences
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An Algorithm for Identification of Treatment-response Biomarkers to Chemotherapies
Invention Summary:In the last decade, several computational methods have been successfully applied to understand cancer initiation and progression through integration of genomic and epigenomic data. However, despite recent advances in discovering a wide array of novel chemotherapy agents, identification of patients with poor and favorable response prior...
Published: 12/8/2021
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Inventor(s): Antonina Mitrofanova, Nusrat Epsi
Keywords(s): Bioinformatics, Biomarkers, Cancer biomarkers, Data Science, Digital Health
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > Software & Algorithms, Technology Classifications > Software & Copyright
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Panel & Software to Predict Therapeutic Resistance in Cancer Treatment
Invention Summary:According to the American Cancer Society, prostate cancer is the second most common malignancy in men and the second-highest cancer-related cause of death in American men. Androgen deprivation therapy (ADT), which reduces or prevents male hormones (androgens) from interacting with cancer cells, has been shown to be beneficial in treating...
Published: 12/8/2021
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Inventor(s): Antonina Mitrofanova, Sukanya Panja
Keywords(s): Bioinformatics, Biomarkers, Cancer biomarkers, Prostate Cancer
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
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