|
High Throughput Library Preparation of Long Genomic DNA Targets
Overall workflow for preparing the LASSO library.
Invention Summary:
Advances in DNA sequencing have led to an exponential increase in the quantity of sequence data, whereas limited achievable maximum gene length (<200 bp) can produce highly biased libraries with constraints on sequence homology....
Published: 7/28/2022
|
Inventor(s): Biju Parekkadan, Lorenzo Tosi
Keywords(s):
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools
|
|
Personalized and Timed Release of Biomolecules
Invention Summary:Protein/peptide-based therapeutics are powerful medications, however their use is often hampered by very short half-lives and the necessity for intravenous or subcutaneous injections.Researchers from Rutgers University and Massachusetts General Hospital have developed a novel method to deliver protein/peptide-based therapeutics via...
Published: 12/8/2021
|
Inventor(s): Biju Parekkadan, Alexandra Burr
Keywords(s): Stem Cells
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Cell Therapy, Technology Classifications > Gene Therapy
|
|
Cellular Reprogramming via Co-culture Bioreactor
Invention Summary: Co-culture systems are a popular method for engineering complex multicellular systems. Specifically, for cell therapy, where one cell population can help differentiate another therapeutic cell population. Current co-culture methods have shown benefits, though there still remains a need for a scalable, integrated system that can maintain...
Published: 12/8/2021
|
Inventor(s): Biju Parekkadan
Keywords(s): Stem Cells
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
|
|
Cell Culture Scale-Up via 3D Bioactive Microcapsule
Capsules are designed to protect cells from shear, non-fouling, and customized for ease-of-use and recovery of cells.
Invention Summary:
Industrial cell culture scale-up is a critical unit operation in biopharmaceutical processes. Culturing adherent cells is particularly challenging, since they can’t simply be cultured in suspension but instead...
Published: 12/8/2021
|
Inventor(s): Biju Parekkadan, Ayesha Aijaz
Keywords(s):
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Research Tools, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Cell Therapy
|
