Personalized and Timed Release of Biomolecules

Invention Summary:

Protein/peptide-based therapeutics are powerful medications, however their use is often hampered by very short half-lives and the necessity for intravenous or subcutaneous injections.


Researchers from Rutgers University and Massachusetts General Hospital have developed a novel method to deliver protein/peptide-based therapeutics via viral-mediated gene delivery or transplantation of genetically engineered cells. The expression of transduced genes and thus secretion/delivery of corresponding protein/peptide therapeutics can be achieved through various ways: 1) as a response to a normal physiological cue for optimal delivery; 2) in response to disease-related molecular signals;  3) in response to an external stimuli.

Market Applications:

- Gene Therapy

- Cell Therapy



- Sustained drug release

- Controlled drug release

- Timed drug release


Intellectual Property & Development Status:

Patent pending. Available for licensing and/or research collaboration.

Patent Information:
For Information, Contact:
Lisa Lyu
Assistant Director
Rutgers University
Stem Cells