Search Results - yon+ebright

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Therapeutics for Tuberculosis: Novel Inhibitors of Mycobacterial RNA Polymerase Invention Summary:Tuberculosis kills nearly 2 million persons each year. One third of the world's population currently is infected with tuberculosis, and the World Health Organization projects that there will be nearly 1 billion new infections by 2020, 200 million of which will result in serious illness, and 35 million of which will result in death.... Published: 12/8/2021   |   Inventor(s): Richard Ebright, Yon Ebright, Soma Mandal Keywords(s): Antibacterial Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics

Therapeutics for Drug-Resistant Bacterial Infections - Myxopyronins Invention Summary:There is an urgent national and international need for new classes of antibacterial agents effective against bacterial pathogens resistant to current antibacterial agents.Myxopyronin (Myx) is a microbially produced antibiotic that inhibits bacterial RNA polymerase through a novel binding site and novel mechanism. Rutgers researchers... Published: 12/8/2021   |   Inventor(s): Richard Ebright, Juan Shen, James Bacci, William Solvible, Christopher Self, Gary Olson, Yon Ebright, Anne-Cecile Hiebel Keywords(s): Antibacterial Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics