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Continuous Process for API Formulation and Manufacturing
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A comparison of dissolution profiles for impregnated ibuprofen (IBU) tablets and direct compression IBU tablets
Invention Summary:
A major challenge in pharmaceutical product development is the formation of homogenous blends containing small amount of active pharmaceutical ingredients (APIs). Poor...
Published: 7/28/2022
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Inventor(s): Fernando Muzzio, Benjamin Glasser, Thamer Omar
Keywords(s): Chemical and petrochemical industry, Manufacturing
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences
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Fine-Tune Cellulose Crystals in Biocomposites
Morphology change from crystalline (I. Pure Cellulose) to amorphous (III. coagulated in water) or semi-crystalline (IV. coagulated in H2O2) Invention Summary:Natural materials such as cellulose or silk can be used in a multitude of applications such as electrolyte batteries, filters, drug delivery systems and scaffolds for tissue engineering. Transforming...
Published: 12/8/2021
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Inventor(s): David De La Cruz, Xiao Hu, Stacy Love, David Verrill
Keywords(s): Biomaterials, Chemical and petrochemical industry, Membranes, Nanotechnology
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
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A Novel, Tailor-Made MOF for Exceptionally Efficient Separation of Propane and Propylene
Invention Summary: Separating mixtures of propane and propylene is often challenging and energy intensive. In industrial settings this separation is typically performed by cryogenic distillation, requiring low temperature and/or pressure. Metal-organic frameworks (MOFs) are emerging as promising low-energy alternatives to energy-intensive distillations,...
Published: 12/8/2021
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Inventor(s): Jing Li, Hao Wang
Keywords(s): Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Nanotechnology
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Novel metal-organic frameworks for efficient separation of alkane isomers
Schematic representation of two-stage MOFs absorbent bed for the separation of alkane mixtures to pure form of each isomer (straight line, mono-branched and di-branched)Invention Summary: The separation of alkane isomers represents a critical yet challenging process in the petrochemical industry to produce high-quality gasoline. As an alternative technology...
Published: 12/8/2021
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Inventor(s): Jing Li, Hao Wang
Keywords(s): Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
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Iridium Catalyst for Dehydrogenative Dimerization of Ethylene to Yield 1,3-Butadiene
Schematic diagram of the catalytic dehydrogenative dimerization of ethylene to butadieneInvention Summary: 1,3-Butadiene is a chemical building block, most notably known for the production of synthetic elastomers and polymers. Traditionally, 1,3-butadiene is produced as a byproduct of naphtha cracking for ethylene production. Due to new sources, ethylene...
Published: 12/8/2021
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Inventor(s): Alan Goldman, Yang Gao
Keywords(s): Catalysts, Chemical and petrochemical industry, Polymers & Composites
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Catalysts, Technology Classifications > Polymers/Composites/Materials
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A Molecular Trap for Capturing Radioactive Organic Iodides from Nuclear Waste
Molecular trap is 340% more efficient than current processesInvention Summary: Rutgers University researchers have developed a metal-organic framework (MOF) molecular trap to remove radioactive organic iodides (ROI) from nuclear waste streams. Nuclear power provides ~11% of the world’s electricity currently. How to safely dispose nuclear waste...
Published: 12/8/2021
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Inventor(s): Jing Li, Baiyan Li
Keywords(s): Chemical and petrochemical industry, Cleaning/Disinfecting Products, Nanotechnology
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
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Thermo-Activated Lubricant Additives for Improving Engine Efficiency and Fuel Economy
Controlled Release Friction Reduction over TimeInvention Summary:Friction modifiers (FMs) have been extensively studied as lubricant additives that could improve lubricity of base oil friction profiles to enhance fuel economy by the petrochemical and automobile industries. There are two classes of FMs, the ash FM (organo-molybdenum molecules) and ashless...
Published: 12/8/2021
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Inventor(s): Kathryn Uhrich, Jonathan Faig, Yingyue Zhang, Shuji LUO, Man KIT NG, Alan SCHILOWITZ, Anne SHOUGH
Keywords(s): Biomaterials, Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
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Synthesis of p-Xylene by Dehydroaromatization of 3-Methyleneheptane obtained from Ethylene
Invention Summary:p-Xylene is mostly produced from cracking of naphtha, but there is a need for new and cost-effective methods for the production. Indeed, conventional p-xylene synthesis requires toluene separation from refinery gasoline streams; performing a disproportionation reaction to yield a benzene fraction and a mixed xylene fraction; and finally...
Published: 12/8/2021
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Inventor(s): Alan Goldman, Andrew Steffens, William Schinski
Keywords(s): Catalysts, Chemical and petrochemical industry, Polymers & Composites
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Catalysts
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Novel Complexes Of N-Heterocyclic Carbenes For Transition-Metal Catalysis
Invention Summary:Palladium-catalyzed cross-coupling reactions are tremendously valuable in the synthesis of small molecules and are among the most important methods for the construction of diverse chemicals. In numerous Pd-catalyzed reactions, NHCs (NHC = N-heterocyclic carbenes) are advantageous as ancillary ligands due to their strong -donation...
Published: 12/8/2021
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Inventor(s): Michal Szostak, Shicheng Shi
Keywords(s): Catalysts, Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Catalysts
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Novel Ligands for Transition-Metal Catalysis
Invention Summary:N-heterocyclic carbenes (NHCs) are tremendously valuable ligands in homogeneous catalysis. IPr (IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) represents the most important NHC. Rutgers scientists have developed novel, sterically bulky, easily accessible NHC ligand IPr# (referred to as “hash” series) that can be...
Published: 12/8/2021
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Inventor(s): Michal Szostak, Qun Zhao, Guangrong Meng, Guangchen Li
Keywords(s): Catalysts, Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Catalysts
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