|
Novel Cationic Amphiphiles Control Biofilm Formation for Bacterial Vaginosis
Cationic amphiphiles greatly inhibits the biofilm formation of the pathogenic bacteria in BV.Cationic Amphiphile Concentration (μM)Invention Summary:Bacterial vaginosis (BV) is a common polymicrobial infection in women of reproductive age, affecting 10-30% of women in developed nations. BV can lead to serious complications such as abortion, premature...
Published: 12/8/2021
|
Inventor(s): Kathryn Uhrich, Allison Faig
Keywords(s): Antibacterial, Biofilm, Biomaterials, Drug Delivery, Personal Care, Cosmeceuticals, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
|
|
Biodegradable and Versatile Copolymers to Promote Wound Healing
Invention Summary:Rutgers scientists have developed a copolymer formulation to stably release salicylic acid (SA). It holds the promise for promoting topical and surgical wound healing, as SA is known to reduce local pain and inflammation as well as potentially prevent fibrous adhesion formation by reducing scar tissue. The release is stable over a...
Published: 12/8/2021
|
Inventor(s): Kathryn Uhrich, Sabrina Snyder
Keywords(s): Biomaterials, Drug Delivery, Neurological disorder & neuropathic pain, Wound healing
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
|
|
Cationic Amphiphile for Antimicrobial Applications
The structure of CAms 5a, 5b, 5c, 8a, 8b, and 8c
Invention Summary:
The development of antibiotic-resistant bacteria is a prevalent concern that has prompted the development of new antimicrobial agents. Naturally-occurring antimicrobial peptides (AMPs) offer advantages over conventional antibiotics due to a reduced development of resistance...
Published: 12/8/2021
|
Inventor(s): Kathryn Uhrich, Yingyue Zhang, Allison Faig, Michael (mikhail) Chikindas
Keywords(s): Antibacterial, Biomaterials, Peptides
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences
|
|
Thermo-Activated Lubricant Additives for Improving Engine Efficiency and Fuel Economy
Controlled Release Friction Reduction over TimeInvention Summary:Friction modifiers (FMs) have been extensively studied as lubricant additives that could improve lubricity of base oil friction profiles to enhance fuel economy by the petrochemical and automobile industries. There are two classes of FMs, the ash FM (organo-molybdenum molecules) and ashless...
Published: 12/8/2021
|
Inventor(s): Kathryn Uhrich, Jonathan Faig, Yingyue Zhang, Shuji LUO, Man KIT NG, Alan SCHILOWITZ, Anne SHOUGH
Keywords(s): Biomaterials, Chemical and petrochemical industry
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
|
|
Versatile Biodegradable, Bioactive-Based Polymers for Topical, Cosmetic and Personal Care Applications
A. Structure of salicylic acid-based polymer and its degradation products.
B. Polymer degradation rates with different linker molecules.
C. Free ferulic acid in aqueous solution is unstable and turns brown after 10 days (left). Ferulic acid-based polymers are stable and aesthetically more pleasing in solution under the same condition (right).
Invention...
Published: 12/8/2021
|
Inventor(s): Kathryn Uhrich, Jonathan Faig, Kervin Smith
Keywords(s): Antibacterial, Biomaterials, Drug Delivery, Personal Care, Cosmeceuticals, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences
|
|
Biodegradable and Biocompatible Bioactive-based Polymers - Versatile Platform Technology
Invention Summary:The Uhrich group at Rutgers University has developed various biodegradable polymers that chemically incorporate bioactive molecules, such as nonsteroidal anti-inflammatory drugs (e.g., salicylic acid), antioxidants (e.g., ferulic acid) and antimicrobials (e.g., carvacrol). Bioactive molecules are incorporated into polymer backbones...
Published: 12/8/2021
|
Inventor(s): Kathryn Uhrich, Jonathan Faig, Kervin Smith
Keywords(s): Antibacterial, Bioengineering scaffolds, Biomaterials, Drug Delivery, Polymers & Composites
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
|
|
Tunable Quantitative Assays
Invention Summary:Scientists at Rutgers have designed a way to simultaneously quantitate target biomarkers and discriminate these biomarkers from closely related molecular entities. By making use of the thermodynamics of competitive differential hybridization, Tunable Quantitation Assays (TQAs) quantify target concentrations and substantially reduce...
Published: 12/8/2021
|
Inventor(s): Kathryn Uhrich
Keywords(s): Biomaterials, Drug Delivery, Inflammation, Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
|
