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Continuous Process for API Formulation and Manufacturing
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A comparison of dissolution profiles for impregnated ibuprofen (IBU) tablets and direct compression IBU tablets
Invention Summary:
A major challenge in pharmaceutical product development is the formation of homogenous blends containing small amount of active pharmaceutical ingredients (APIs). Poor...
Published: 7/28/2022
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Inventor(s): Fernando Muzzio, Benjamin Glasser, Thamer Omar
Keywords(s): Chemical and petrochemical industry, Manufacturing
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences
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Novel System for High-Yield Production of Proteins and Protein Domains
Invention Summary:The synthesis of recombinant proteins using prokaryotic expression systems has been instrumental in producing valuable reagents for biomedical research and commercial products. However, the majority of in vivo expression systems have inherent limitations in most applications – including low yields, poor quality of the expressed...
Published: 12/8/2021
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Inventor(s): Gaetano Montelione, Stephen Anderson, Yuanpeng Huang, Thomas Acton
Keywords(s): Drug Discovery/Screening, Manufacturing, Peptides
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools
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Coating with Self-Limiting Electrospray Deposition
Invention Summary: Researchers at Rutgers University have developed a scalable technique for depositing microscale coatings of a wide variety of materials and composites onto complex 3D additive or micromachined structures. The new coating process, based on self-limiting electrospray deposition (SLED), once deposited on the surface of a target...
Published: 12/8/2021
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Inventor(s): Jonathan Singer, Howon Lee
Keywords(s): Manufacturing
Category(s): Technology Classifications > Physical Sciences & Engineering
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Damage Resistant Glass-Ceramic
This material has better hardness and crack resistance than any commercially available glassInvention Summary: Rutgers University researchers have developed an Al2O3 rich damage resistant glasses and glass-ceramics, which exhibit Vickers hardness of >7 GPa and do not crack at loads as high as 2000 gf (19.6 N). The resistance to fracture is one of...
Published: 12/8/2021
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Inventor(s): Ashutosh Goel
Keywords(s): Glass & Ceramics, Manufacturing
Category(s): Technology Classifications > Physical Sciences & Engineering
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Continuous Sheet Folding Machine with Microfolding Technology
Invention Summary:Folded materials are useful in packaging, sandwich structures, floor boards, car bumpers and other applications where requirements pertaining to shock, vibration, energy absorption, and/or a high strength-to-weight ratio including volume reduction must be met. Folding flat sheets of material into intricate three-dimensional structures...
Published: 12/8/2021
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Inventor(s): Elsayed Elsayed, Dan Kling, Basily Basily
Keywords(s): Machines & Instruments, Manufacturing
Category(s): Technology Classifications > Physical Sciences & Engineering
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Method for Sintering Ultrahigh Melting Temperature Covalent Non-oxide Ceramics
Parallel plate capacitor configuration used to apply an electric field and to achieve low-temperature sintering of a non-oxide ceramic (B4C) Invention Summary: Bulk and composite structural ceramics can be fabricated by sintering, forming particulate matter into a desired shape and then subjecting the formed body to high temperatures (2/3 of the...
Published: 12/8/2021
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Inventor(s): Thomas Tsakalakos, Enver Akdoğan, Ilyas Savkliyildiz, Hulya Bicer, William Paxton, Bart Visser, Lawrence Kabacoff
Keywords(s): Glass & Ceramics, Manufacturing
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
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Scalable Multiple Inverse-Diffusion Flame Synthesis of Graphene, Syngas and Liquid Fuel & Fabrication of Diamond-Reinforced Composites
A) A schematic multiple inverse-diffusion flames burner. B) Raman spectrum of the few-layer graphene (FLG) on Ni. C) HRTEM image of the FLG. The bottom right insert shows the electron diffraction pattern of the graphene sheet. The top left insert shows resolution magnified image of the graphitic lattice. Invention Summary:Carbon-based nanostructures...
Published: 12/8/2021
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Inventor(s): Bernard Kear, Stephen Tse, Nasir Memon
Keywords(s): Graphene technology, Manufacturing
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
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