Search Results - gaetano+montelione

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Novel System for High-Yield Production of Proteins and Protein Domains Invention Summary:The synthesis of recombinant proteins using prokaryotic expression systems has been instrumental in producing valuable reagents for biomedical research and commercial products. However, the majority of in vivo expression systems have inherent limitations in most applications – including low yields, poor quality of the expressed... Published: 12/8/2021   |   Inventor(s): Gaetano Montelione, Stephen Anderson, Yuanpeng Huang, Thomas Acton Keywords(s): Drug Discovery/Screening, Manufacturing, Peptides Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools

High Efficiency Isotope Enriched Protein Production Systems Isotopic Enrichment of Tryptic FragmentsInvention Summary:Rutgers scientists have developed two Single Protein Production (SPP)-based systems to obtain high levels of specific isotopically enriched proteins: an independently inducible system (cSPP(tet)) and an amino acid auxotroph-based dual inducible system. The proprietary SPP system, developed at... Published: 12/8/2021   |   Inventor(s): Monica Roth, William Schneider, Gaetano Montelione, Masayori Inouye, Yeufeng Tang Keywords(s): Proteins Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools