Search Results - proteins

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Novel ChABC formulation with machine learning-guided automation
​ ​ Invention Summary: Spinal cord injury (SCI) leads to the formation of scar tissue. The scarring leads to the toughening of the extracellular matrix, or the cellular environment. One of the major concerns of SCI is the prevention of neuronal connection recovery, which can lead to paralysis or reduced control of the nervous system. For...
Published: 8/18/2022   |   Inventor(s): Adam Gormley, Matthew Tamasi, Shashank Kosuri, Michael Webb, Carlos Borca, Roshan Patel
Keywords(s): Biomaterials, Polymers & Composites, Proteins, Spinal Cord
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Software & Algorithms, Technology Classifications > Therapeutics
Use of purified Epichloë festucae antifungal protein for dollar spot control on turfgrass
­ ​ ​ Invention Summary: The dollar spot disease is a major challenge for turfgrass fields, especially golf courses. The commonly used solution to control this disease is fungicides, which can be hazardous and limited in effectiveness; thus, the need for an alternative solution is imminent. Rutgers researchers in the department of...
Published: 6/29/2022   |   Inventor(s): Faith Belanger, Bruce Clarke, Patrick Fardella
Keywords(s): Pest control, Proteins
Category(s): Technology Classifications > Agriculture, Technology Classifications > Ag Biotech
Novel Computational Tool for Understanding Protein Interactions and Generating Energy Maps
Generation of the interior and exterior residues, which are predominantly hot and cold, respectively (red/salmon = high, white = middle, cyan/blue = low μ-factors), in a catalytic site of an enzyme using the novel computational model. Invention Summary: Most computational models rely on large numbers of weak interactions to describe protein energetics....
Published: 12/8/2021   |   Inventor(s): Lawrence Williams
Keywords(s): Proteins
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > Research Tools
A Novel Vaccine Candidate Against Fungal Infection
Vaccination with a heat-killed mutant strain offers cross-protection against diverse fungal infections in a mouse model, significantly improving survival. A.) Mice vaccinated at different doses show higher survival rates when challenged with a wild strain (H99) of fungus. B.) Vaccinated mice are protected from infection by C. gattii R265 and have significantly...
Published: 12/8/2021   |   Inventor(s): Chaoyang Xue, Amariliz Rivera
Keywords(s): Proteins
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Vaccine
A Novel Diagnostic Assay for Predicting Patients’ Resistance to mTOR Kinase Inhibitors
Invention Summary:Mechanistic Target of Rapamycin (mTOR) is a highly conserved serine/thereonine protein kinase that plays a crucial role as part of two distinct kinase complexes, mTOR1C and mTOR2C, to regulate cell growth and metabolism. Abnormal activation of mTOR has been implicated in the pathogenesis of several cancers, type 2 diabetes, obesity,...
Published: 12/8/2021   |   Inventor(s): Steven Zheng
Keywords(s): Proteins
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics
High Efficiency Isotope Enriched Protein Production Systems
Isotopic Enrichment of Tryptic FragmentsInvention Summary:Rutgers scientists have developed two Single Protein Production (SPP)-based systems to obtain high levels of specific isotopically enriched proteins: an independently inducible system (cSPP(tet)) and an amino acid auxotroph-based dual inducible system. The proprietary SPP system, developed at...
Published: 12/8/2021   |   Inventor(s): Monica Roth, William Schneider, Gaetano Montelione, Masayori Inouye, Yeufeng Tang
Keywords(s): Proteins
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools
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