Search Results - youyi+peng

2 Results

Sort By: Published Date Updated Date Title ID Descending Ascending

Sigma-1 Receptor Antagonists – Non-Addictive Pain Management Invention Summary: The sigma 1 receptor (S1R), a molecular chaperone protein located in the endoplasmic reticulum and plasma membranes, plays important roles in various pathological disorders including pain. The potential commercial applications of novel S1R antagonists are twofold: 1) as stand-alone therapy for the treatment of chronic neuropathic... Published: 12/8/2021   |   Inventor(s): William Welsh, Youyi Peng Keywords(s): Antiviral, Neurological disorder & neuropathic pain, Small molecules Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics

Small Molecule Extracellular Inhibitors of TAM Receptors for Cancer Therapy Invention Summary:The TAM receptors (Tyro3, Axl, and Mertk) are a family of three homologous receptor tyrosine kinases (RTKs) that play important roles in tissue homeostasis, immune response, and the resolution of inflammation. Besides the intracellular catalytic kinase domain common to all kinases, the TAMs uniquely contain an extracellular domain... Published: 12/8/2021   |   Inventor(s): William Welsh, Raymond Birge, Vladyslav Kholodovych, Youyi Peng, Stanley Kimani, Thomas Comollo Keywords(s): Anti-cancer, Brain Cancer, Breast Cancer, Cancer biomarkers Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics