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A New Method to Enhance Lung Cancer Treatment
Summary:
Non-Small Cell Lung Carcinoma (NSCLC) is the most common type of lung cancer. Small molecule Tyrosine Kinase (TK) Inhibitors acting on the Epidermal Growth Factor Receptors (EGFRs) are standard therapies for patients with NSCLC harboring EGFR-TK inhibitor-sensitizing mutations. However, fewer than 10 % of patients with NSCLC benefit from...
Published: 12/8/2021
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Inventor(s): Tamara Minko, Olga Garbuzenko
Keywords(s): Drug Delivery, Nanoparticles, Nanotechnology
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Cancer, Technology Classifications > Nanotechnology
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Film Forming Foam (FFF) for Burn Wounds/Burnflex
Invention Summary:
Many of the available burn dressings on the market use latex, PVC or polyurethane as means of barrier-like components to protect the patient from outside elements. The current use of these components presents a problem of waste and contamination. Other available options in the market are hydrogel-based dressings that may...
Published: 12/8/2021
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Inventor(s): Maricely RamÃrez-Hernández, Tewodros Asefa, Jeffrey Boyd, Javiera Norambuena-Morales
Keywords(s): Antibacterial, Drug Delivery, Nanoparticles, Nanotechnology, Wound healing
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Nanotechnology, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Biomaterials, Technology Classifications > Consumer & Household Goods
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Novel Nanomaterial for Prolonged and Sustained Antibacterial Efficacy
a) BAC release profile at pH 4.0, 5.0, 6.5, and 7.4. b) The percentage of S. aureus survival upon exposure to BAC loaded nanoparticles after 0, 3, and 6 hours.Invention Summary: Quaternary ammonium cationic (QAC) surfactants are one of the preferred choices for antibacterial applications. The compounds are water and oil soluble, and they cover a broad...
Published: 12/8/2021
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Inventor(s): Tewodros Asefa, Viktor Dubovoy, Anjani Ganti, Jeffrey Boyd
Keywords(s): Antibacterial, Nanoparticles, Nanotechnology, Personal Care, Cosmeceuticals
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Nanotechnology, Technology Classifications > Healthcare & Life Sciences
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Nanotechnology-based Method for Treatment of Primary Ovarian Cancer and Prevention of Metastases
Two-in-one: Combined nanocarrier based targeted chemo and gene therapy1. Cellular penetration of naked siRNA (green) and siRNA delivered by nanocarrier (red), 2. Treatment of mice bearing metastatic ovarian cancer. a. Mice bearing xenografts of human metastatic cancer and histology of tumor tissue (before treatment), b. Mice bearing xenografts of human...
Published: 12/8/2021
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Inventor(s): Tamara Minko, Olga Garbuzenko, Oleh Taratula, Lorna RodrigueZ-Rust
Keywords(s): Anti-cancer, Nanoparticles, Nanotechnology
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Biomaterials
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Nanoparticle Delivery System for the Treatment of Non-Small Cell Lung Cancer and Targeted Cancer Therapy
Invention Summary:Rutgers scientists have invented a novel treatment strategy that relates to an intravenously (“IV”) administered lung targeted nanoparticle (NP)/ gel microparticle (GMP) delivery system for the treatment of non-small cell lung cancer (NSCLC). The delivery system delivers the chemotherapeutic agent camptothecin (CPT) along...
Published: 12/8/2021
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Inventor(s): Patrick Sinko
Keywords(s): Anti-cancer, Drug Delivery, Nanoparticles
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Biomaterials
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Oral Delivery of Therapeutics and Diagnostics using Peptide Ligands
Invention Summary:Intestinal uptake and absorption of orally administered drugs has been a challenge in the field of drug development and therapeutics research. Rutgers scientists have recently invented a novel mechanism to achieve increased absorption of molecules and to enhance their bioavailability via oral delivery. This invention facilitates the...
Published: 12/8/2021
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Inventor(s): Patrick Sinko
Keywords(s): Drug Delivery, Nanoparticles, Peptides
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Biomaterials, Technology Classifications > Therapeutics
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Multifunctional Rare Earth-Based Biophotonic Composites
Image showing use of bio-encapsulated Rare Earth (RE) doped nanoparticles targeting melanoma cells.Invention Summary:Researchers at Rutgers University have developed new rare earth (RE)-based light-emitting, multifunctional composites for use in various biomedical applications, such as non-invasive imaging, image–guided interventions, drug tracking...
Published: 12/8/2021
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Inventor(s): Prabhas Moghe, Richard Riman, Charles Roth, MeI-Chee Tan, Dominik Naczynski
Keywords(s): Imaging, Nanoparticles
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Imaging, Technology Classifications > Nanotechnology
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Nanotechnology Approach for Inhalation Treatment
of Pulmonary (Lung) Fibrosis
Inhalation TreatmentInvention Summary:Idiopathic Pulmonary Fibrosis (IPF), the spontaneous development of scar tissue within the lungs, is a progressive fibrotic disease which impairs the lung’s ability to get oxygen. To date, its pathogenesis remains elusive and the survival time of patients is between three and five years. Pirfenidone, an orally...
Published: 12/8/2021
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Inventor(s): Tamara Minko, Vera Ivanova, Olga Garbuzenko
Keywords(s): Nanoparticles, Nanotechnology, Respiratory Disease
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
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