|
“Off-the-shelf” CAR-NK cells for SARS-CoV-2 targeting in COVID-19 treatment
S309-CAR cells show higher lysis of cells transfected with the RBD of the SARS-CoV-2 spike protein compared to control.
Invention Summary:
COVID-19 remains a pandemic and a critical medical concern across the world. Patients with severe symptoms who are admitted into the ER have grim prognosis and are sometimes faced with expensive and limited...
Published: 12/8/2021
|
Inventor(s): Dongfang Liu, Minh Ma, Saiaditya Badeti
Keywords(s): Antiviral, Bioengineering scaffolds
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > COVID-19
|
|
“Off-the-shelf” CAR-NK cells for enhanced SARS-CoV-2 targeting in COVID-19 treatment
CR3022-CAR cells have greater lysis of cells transfected with the RBD of the SARS-CoV-2 spike protein compared to control.
Invention Summary:
COVID-19 remains a pandemic and a critical medical concern across the world. Patients with severe symptoms are admitted into the ER have grim prognosis and have expensive limited treatment options. A large...
Published: 12/8/2021
|
Inventor(s): Dongfang Liu, Minh Ma, Saiaditya Badeti
Keywords(s): Antiviral, Bioengineering scaffolds
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19, Technology Classifications > Therapeutics, Technology Classifications > Cell Therapy
|
|
Deposition of Microscale Coatings by Self-Limiting Electrospray
a. Overview of thickness-limited electrospray deposition (ESD). Electrostatically-driven spray creates a charged film which redirects charged incident droplets. b. and c. SEM images of spray results, illustrating the wide range of morphologies and particle size which can be obtained with this method(b: nanowires, c: hollow spheres).Invention Summary:...
Published: 12/8/2021
|
Inventor(s): Jonathan Singer, Lin Lei
Keywords(s): Drug Delivery
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > COVID-19, Technology Classifications > Medical Devices, Technology Classifications > Vaccine
|
|
Nanowell Array Sensor Chip for Biosensing in Blood Samples
Entire multiwell plate chip and a schematic view of the 2-μm nanowell array sensor. The sensor is comprised of an array of 25 nanowells etched on the overlapping electrode surface.
Invention Summary:
The current gold-standard for protein quantification in laboratory tests is enzyme linked immunosorbent assay (ELISA), which typically relies on...
Published: 7/28/2022
|
Inventor(s): Mehdi Javanmard, Pengfei Xie, Mark Allen, Wen Shen, Naixin Song
Keywords(s): Biosensor, Immunoassay
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Devices, Technology Classifications > Diagnostics, Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences
|
|
DNA Nanodevices for Point-of-Care Testing
DNA nanodevice can detect 0.1 nm microRNAInvention Summary: Point-of-Care (POC) testing is defined as a simple operated, easy-to-read, rapid and low-cost medical diagnosis that can be used by non-specialists at home, in the field or on an ambulance. It provides timely diagnostic results, enabling early diagnosis of diseases, protective therapy and rapid...
Published: 12/8/2021
|
Inventor(s): Jinglin Fu, Sung Won Oh, Adriana Pereira
Keywords(s): Bioengineering scaffolds, Biomarkers, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Diagnostics, Technology Classifications > COVID-19, Technology Classifications > Research Tools, Technology Classifications > Infectious Disease
|
|
Novel Fusion Polypeptides as Antiviral and Cancer Therapeutics
Antitumor and antiviral effects of the fusion IFN-β-IFN-λ in vivoInvention Summary:Type I and Type III interferons (IFNs) are well known for their potent broad-spectrum antiviral activities. In addition, these pluripotent cytokines can also regulate cell growth and differentiation, tissue homeostasis, angiogenesis, as well as immune and...
Published: 12/8/2021
|
Inventor(s): Sergei Kotenko, Joan Durbin
Keywords(s): Anti-cancer, Antiviral
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19
|
|
Low-Cost, Flexible, Paper-Based Plasma Sanitizer
Low-Cost, Flexible, Paper-Based Plasma SanitizerInvention Summary: Healthcare-associated infections (HAIs) are a major challenge facing disease control organizations and healthcare providers worldwide. In 2011, there were 721,800 cases of HAIs reported in the US, with 75,000 patients ultimately dying from the infections. Because a leading cause of HAIs...
Published: 12/8/2021
|
Inventor(s): Aaron Mazzeo, Jingjin Xie, Qiang Chen
Keywords(s): Antibacterial, Antiviral, Cleaning/Disinfecting Products, Electronics, Flexible electronics, Packaging, Wound healing
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > COVID-19, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics, Technology Classifications > Electronics/Semiconductor
|
|
Risk Terrain Modeling Diagnostics Software (RTMDx)
Invention Summary:
Researchers at Rutgers who originally developed Risk Terrain Modeling, a methodology for diagnosing spatial crime vulnerabilities, have launched the Risk Terrain Modeling Diagnostics (RTMDx) Utility software. RTMDx helps to identify and communicate environmental factors associated with specific events. Reports produced can be used...
Published: 12/8/2021
|
Inventor(s): Joel Caplan, Leslie Kennedy
Keywords(s):
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms, Technology Classifications > COVID-19
|
